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Article

Positive selection of Iris, a retroviral envelope-derived host gene in Drosophila melanogaster.

PLoS genetics - 1 Oct 2005

Malik Harmit S, Henikoff Steven

Abstract excerpt

Eukaryotic genomes can usurp enzymatic functions encoded by mobile elements for their own use. A particularly interesting kind of acquisition involves the domestication of retroviral envelope genes, which confer infectious membrane-fusion ability to retroviruses. So far, these examples have been limited to vertebrate genomes, including primates where the domesticated envelope is under purifying selection to...

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PMID: 16244705
DOI: 10.1371/journal.pgen.0010044
PMCID: PMC1262188

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