Article
[DNA methylation analysis in environmental and occupational cancer research].
Giornale italiano di medicina del lavoro ed ergonomia - 1 Jan 2000
Baccarelli A, Marinelli B, Bollati V, Albetti B, Consonni D, Bonzini M, Pesatori A C, Bertazzi P A
Abstract excerpt
The present paper reviews recent laboratory methods and experimental evidence concerning epigenetic biomarkers involved in carcinogenesis mechanisms. We introduce DNA methylation and its role in gene expression control. DNA methylation analysis may allow to identify early changes leading to cancer and other chronic diseases. We describe here strategies for laboratory analyses and their possible applications. We...
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