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Article

DNA Methylation in Radiation-Induced Carcinogenesis: Experimental Evidence and Clinical Perspectives.

Critical reviews in oncogenesis - 1 Jan 2018

Miousse Isabelle R, Ewing Laura E, Kutanzi Kristy R, Griffin Robert J, Koturbash Igor

Abstract excerpt

Ionizing radiation is a valuable tool in many spheres of human life. At the same time, it is a genotoxic agent with a well-established carcinogenic potential. Progress achieved in the last two decades has demonstrated convincingly that ionizing radiation can also target the cellular epigenome. Epigenetics is defined as heritable changes in the expression of genes that are not due to alterations of DNA sequence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Repetitive Sequences, Nucleic Acid

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Identifiers

PMID: 29953365
DOI: 10.1615/CritRevOncog.2018025687
PMCID: PMC6369919

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