Article
Disruption of LRG1 inhibits mother-daughter separation in Saccharomyces cerevisiae.
Yeast (Chichester, England) - 30 Oct 2005
Svarovsky Michael J, Palecek Sean P
Abstract excerpt
LRG1, previously characterized as a Rho-GAP that regulates beta-1,3-glucan synthesis, was identified using a filtration screen designed to isolate genes that promote cell aggregation in Sigma1278b Saccharomyces cerevisiae. Disruption of LRG1 in haploid cells resulted in enhanced invasive growth and a strain-specific 'clustered' phenotype that is a consequence of failed separation of mother and daughter cells....
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