Woc gene mutation causes 20E-dependent alpha-tubulin detyrosination in Drosophila melanogaster.

Abstract excerpt

The mutation without children(rgl) (woc(rgl)) is a newly described ecdysone-deficient Drosophila mutant. The woc(rgl) mutant larvae show developmental arrestment at the late larval stage and fail to form a puparium due to the failure of the ring gland to secret normal levels of ecdysone. Although a 6.8-kb woc gene transcript encoding a 187-kDa potential transcription factor has been cloned and lack of a specific...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Drosophila melanogaster
• Share to Drosophila Proteins
• Share to Electrophoresis, Gel, Two-Dimensional