Article
Mutation of a Cuticle Protein Gene, BmCPG10, Is Responsible for Silkworm Non-Moulting in the 2nd Instar Mutant.
PloS one - 1 Jan 2016
Wu Fan, Wang Pingyang, Zhao Qiaoling, Kang Lequn, Xia Dingguo, Qiu Zhiyong, Tang Shunming, Li Muwang, Shen Xingjia, Zhang Guozheng
Abstract excerpt
In the silkworm, metamorphosis and moulting are regulated by ecdysone hormone and juvenile hormone. The subject in the present study is a silkworm mutant that does not moult in the 2nd instar (nm2). Genetic analysis indicated that the nm2 mutation is controlled by a recessive gene and is homozygous lethal. Based on positional cloning, nm2 was located in a region approximately 275 kb on the 5th linkage group by...
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