Article
Tracing the evolution of hepatitis C virus in the United States, Japan, and Egypt by using the molecular clock.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Oct 2005
Mizokami Masashi, Tanaka Yasuhito
Abstract excerpt
The molecular clock has been a very powerful tool in looking back at the epidemic spread of HCV infection in the United States (US) and Japan, as well as in Egypt. This analysis estimates that the growth of the US HCV genotype 1a (HCV-1a)-infected population occurred around 1960, at least 30 years later than the widespread introduction of HCV-1b into the Japanese population. In Japan, the estimated effective...
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