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Article

Molecular Evolution and Phylodynamics of Acute Hepatitis B Virus in Japan.

PloS one - 1 Jan 2016

Lin Serena Y C, Toyoda Hidenori, Kumada Takashi, Liu Hsin-Fu

Abstract excerpt

Hepatitis B virus (HBV) is prevalent worldwide and causes liver diseases, including acute and chronic hepatitis. Ten HBV genotypes (A-J) with distinct geographic distributions have been reported. Cases of acute HBV infection with genotype A have increased in Japan nationwide since the 1990s, mainly through sexual transmission. To investigate the molecular evolution and phylodynamics of HBV genotypes, we collected...

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Identifiers

PMID: 27280441
DOI: 10.1371/journal.pone.0157103
PMCID: PMC4900519

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