Article
The nude gene and the skin.
Experimental dermatology - 1 Oct 2001
Schlake T
Abstract excerpt
The nude mutation has been known for a long time. Nevertheless, the gene responsible for the defect has been identified only recently. It encodes a transcriptional activator of the family of forkhead proteins mainly expressed in thymic epithelium and distinct keratinocyte populations in the epidermis and hair follicles. The present review focuses on the molecular and functional characterization of the nude gene...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Biological Evolution
- Cloning, Molecular
- DNA-Binding Proteins
- Forkhead Transcription Factors
- Gene Expression
- Genome
- Mice
- Mice, Nude
- Molecular Sequence Data
- Mutation
- Skin
- Transcription Factors
