Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analytical Validation and Interobserver Reproducibility of EnzMet GenePro

13 Oct 2005

Abstract excerpt

Fluorescence in situ hybridization (FISH) has both excellent sensitivity and specificity in detecting HER2 gene amplification in invasive breast carcinoma. FISH has not been widely implemented in clinical practice because of reagent costs and the special instrumentation and expertise required to perform and integrate the assay. Immunohistochemistry (IHC) for HER2 protein is widely used, but false-positive and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Biosensing Techniques and Applications
Share to HER2/EGFR in Cancer Research
Share to Monoclonal and Polyclonal Antibodies Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16224218
DOI: 10.1097/01.pas.0000172294.67409.4f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analytical Validation and Interobserver Reproducibility of EnzMet GeneProPMID 16224218Read ↗

Validation of Dual-Color Dual In Situ Hybridization for HER2/neu Gene in Breast CancerSemantic proximity Read ↗

Out of the darkness and into the light: bright field in situ hybridisation for delineation of ERBB2 (HER2) status in breast carcinoma.Semantic proximity Read ↗

Chromogenic In Situ HybridizationSemantic proximity Read ↗

A UK NEQAS ISH Multicenter Ring Study Using the Ventana <i>HER2</i> Dual-Color ISH AssaySemantic proximity Read ↗

Computer-aided scoring of erb-b2 receptor tyrosine kinase 2 (HER2) gene amplification status in breast cancerSemantic proximity Read ↗

Evaluation of analytical accuracy of HER2 status in patients with breast cancerSemantic proximity Read ↗

Emerging Technologies for Assessing HER2 AmplificationSemantic proximity Read ↗

Comparison of different commercial kits for HER2 testing in breast cancer: looking for the accurate cutoff for amplificationSemantic proximity Read ↗

Development of automated brightfield double In Situ hybridization (BDISH) application for HER2 gene and chromosome 17 centromere (CEN 17) for breast carcinomas and an assay performance comparison to manual dual color HER2 fluorescence In Situ hybridization (FISH)Semantic proximity Read ↗

High Concordance Between Two Companion Diagnostics TestsSemantic proximity Read ↗

Evaluation of HER-2/neu Gene Amplification and Overexpression: Comparison of Frequently Used Assay Methods in a Molecularly Characterized Cohort of Breast Cancer SpecimensSemantic proximity Read ↗

HER2 Positivity in Breast Carcinoma: A Comparison of Chromogenic In Situ Hybridization With Fluorescence In Situ Hybridization in Tissue Microarrays, With Targeted Evaluation of Intratumoral Heterogeneity by In Situ HybridizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.