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Comparison of different commercial kits for HER2 testing in breast cancer: looking for the accurate cutoff for amplification

1 Oct 2007

Abstract excerpt

INTRODUCTION: Accurate determination of human epidermal growth factor receptor 2 (HER2) status is essential for optimal patient management with trastuzumab (Herceptin). However, standard guidelines do not specify a particular commercial kit, antibody or probe for testing, and discrepancies arise from variability between kits. The aim of this study was to compare the accuracy of four commercially available...

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PMID: 17908324
DOI: 10.1186/bcr1770

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