Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Age at onset and familial risk for major depression in a Swedish national twin sample.

Psychological medicine - 1 Nov 2005

Kendler Kenneth S, Gatz Margaret, Gardner Charles O, Pedersen Nancy L

Abstract excerpt

BACKGROUND: In many biomedical disorders, early age at onset (AAO) is an index of high liability to illness which is manifest by an increased risk of illness in relatives. Most but not all prior studies report such a pattern for major depression (MD). METHOD: Lifetime MD and AAO were assessed at personal interview using modified DSM-III-R criteria in 13864 twin pairs, including 4229 onsets of MD, from the Swedish...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Depressive Disorder
Share to Family

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Proportional Hazards Models

Share to Registries

Share to Sweden

Share to Twins, Dizygotic

Share to Twins, Monozygotic

Source

Identifiers

PMID: 16219115
DOI: 10.1017/S0033291705005714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Age at onset and familial risk for major depression in a Swedish national twin sample.PMID 16219115Read ↗

Delineation of two genetic pathways to major depression.Semantic proximity Read ↗

Clinical characteristics of major depression that predict risk of depression in relatives.Semantic proximity Read ↗

Age of onset and family history as indicators of polygenic risk for major depression.Semantic proximity Read ↗

Dissecting the genetic heterogeneity of depression through age at onset.Semantic proximity Read ↗

The temporal relationship of the onsets of alcohol dependence and major depression: using a genetically informative study design.Semantic proximity Read ↗

Familial risk and heritability of depression by age at first diagnosis in Danish twins.Semantic proximity Read ↗

The joint effects of genetic liability and the death of close relatives on risk for major depression and alcohol use disorder in a Swedish national sample.Semantic proximity Read ↗

Genetic markers for depressive disorders with earlier age at onset.Semantic proximity Read ↗

Age at onset as an index of genetic heterogeneity in major psychiatric and substance use disorders.Semantic proximity Read ↗

Stressful life events, genetic liability, and onset of an episode of major depression in women.Semantic proximity Read ↗

A Hospital-Based Twin Register of the Heritability of DSM-IV Unipolar DepressionSemantic proximity Read ↗

The interplay of familial depression liability and adverse events in predicting the first onset of depression during a 10-year follow-up.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.