Article
Breast cancer and ovarian cancer genetics.
Journal of long-term effects of medical implants - 1 Jan 2005
Edlich Richard F, Winters Kathryne L, Lin Kant Y
Abstract excerpt
Breast and ovarian cancers are the second and fifth leading causes of cancer death, respectively, among women in the United States. Individuals with breast cancer have a 20--30% chance of having at least one relative with the disease. However, only 5--10% of the cases are a direct result of germline mutations in highly penetrable genes, such as BRCA1 and BRCA2 (BRCA1/2) as well as genes TP53 and PTEN. Since 1996,...
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