Article
Association of CACNA1C and SYNE1 in offspring of patients with psychiatric disorders.
Psychiatry research - 30 Nov 2016
Gassó Patricia, Sánchez-Gistau Vanessa, Mas Sergi, Sugranyes Gisela, Rodríguez Natalia, Boloc Daniel, de la Serna Elena, Romero Soledad, Moreno Dolores, Moreno Carmen, Díaz-Caneja Covadonga M, Lafuente Amalia, Castro-Fornieles Josefina
Abstract excerpt
Schizophrenia (SZ) and bipolar disorder (BD) are severe mental diseases associated with cognitive impairment, mood disturbance, and psychosis. Both disorders are highly heritable and share a common genetic background. The present study assesses, for the first time, differences in genotype frequencies of polymorphisms located in genes involved in neurodevelopment and synaptic plasticity between genetic high-risk...
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