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Article

Evidence for proprotein convertase activity in the endoplasmic reticulum/early Golgi.

FEBS letters - 24 Oct 2005

Salvas Alexandre, Benjannet Suzanne, Reudelhuber Timothy L, Chrétien Michel, Seidah Nabil G

Abstract excerpt

Processing of precursor proteins by the proprotein convertases is thought to occur mainly in the trans-Golgi network or post-Golgi compartments. Such cleavage is inhibited by the prosegment of the convertases. During our studies of the use of the inhibitory prosegment of PC1, we noticed that a construct containing the prosegment fused to the C-terminal secretory granule sorting domain was cleaved in the...

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Identifiers

PMID: 16213495
DOI: 10.1016/j.febslet.2005.09.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Evidence for proprotein convertase activity in the endoplasmic reticulum/early Golgi.PMID 16213495Read ↗

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