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Article

Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Dec 2005

Caspersen Casper, Wang Ning, Yao Jun, Sosunov Alexander, Chen Xi, Lustbader Joyce W, Xu Hong Wei, Stern David, McKhann Guy, Yan Shi Du

Abstract excerpt

Although amyloid-beta peptide (Abeta) is the neurotoxic species implicated in the pathogenesis of Alzheimer's disease (AD), mechanisms through which intracellular Abeta impairs cellular properties, resulting in neuronal dysfunction, remain to be clarified. Here we demonstrate that intracellular A...

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PMID: 16210396
DOI: 10.1096/fj.05-3735fje

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16210396-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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