Article
Role of mitochondrial dysfunction in Alzheimer's disease.
Journal of neuroscience research - 1 Nov 2002
Castellani Rudy, Hirai Keisuke, Aliev Gjumrakch, Drew Kelly L, Nunomura Akihiko, Takeda Atsushi, Cash Adam D, Obrenovich Mark E, Perry George, Smith Mark A
Abstract excerpt
Abnormalities in mitochondrial function relate to the spectrum of pathological changes seen in Alzheimer's disease. Here we review the causes and consequences of mitochondrial disturbances in Alzheimer's disease as well as how this information might impact on therapeutic approaches to this disease.
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