Article
From genes to decisions: evolving views of genotype-based management in MEN 2.
Cancer treatment and research - 1 Jan 2004
Mulligan Lois M
Abstract excerpt
Diagnosis and management of MEN 2 has evolved considerably since the identification of the underlying disease mutations in the RETproto-oncogene. Presymptomatic detection and prophylactic surgical intervention are now the accepted standard of care. The strong correlation of disease phenotype and mutation genotype has already also allowed us to develop mutation-guided management strategies to optimize time ot...
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