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Article

Hypermethylation of the TPEF/HPP1 Gene in Primary, Metastatic Colorectal Cancers

1 Aug 2005

Abstract excerpt

The role of promoter methylation in the process of cancer cell metastasis has, however, not yet been studied. Recently, methylation of the TPEF (transmembrane protein containing epidermal growth factor and follistatin domain) gene was reported in human colon, gastric, and bladder cancer cells. Using the Methylight assay, TPEF/HPP1 gene methylation was assessed in primary colorectal cancers (n = 47), matched...

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Share to Colorectal Cancer Treatments and Studies
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PMID: 16207479
DOI: 10.1593/neo.05235

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