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Article

Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice.

Genome biology - 1 Jan 2005

Huang Shixia, Li Yi, Chen Yidong, Podsypanina Katrina, Chamorro Mario, Olshen Adam B, Desai Kartiki V, Tann Anne, Petersen David, Green Jeffrey E, Varmus Harold E

Abstract excerpt

BACKGROUND: In human breast cancer normal mammary cells typically develop into hyperplasia, ductal carcinoma in situ, invasive cancer, and metastasis. The changes in gene expression associated with this stepwise progression are unclear. Mice transgenic for mouse mammary tumor virus (MMTV)-Wnt-1 exhibit discrete steps of mammary tumorigenesis, including hyperplasia, invasive ductal carcinoma, and distant...

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Share to Gene Expression Regulation, Neoplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mammary Glands, Animal

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Source

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Identifiers

PMID: 16207355
DOI: 10.1186/gb-2005-6-10-r84
PMCID: PMC1257467

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