Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Crystals in hand.

Arthritis research & therapy - 1 Jan 2005

Loughlin John

Abstract excerpt

A genetic association of the ENPP1 gene with primary hand osteoarthritis was recently reported in this journal. ENPP1 encodes an enzyme that regulates soft tissue calcification. The study as it stands is far from complete because the actual causal variant(s) within ENPP1 has not been identified and no functional study on the activity of the enzyme in hand osteoarthritis was presented. Nevertheless, the study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 6
Share to Crystallization
Share to Diphosphates

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Osteoarthritis

Share to Phosphoric Diester Hydrolases

Share to Pyrophosphatases

Share to Radiography

Share to Russia

Source

Open in PubMed Open full text

Identifiers

PMID: 16207345
DOI: 10.1186/ar1807
PMCID: PMC1257447

Genes

ENPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Crystals in hand.PMID 16207345Read ↗

Genetics of digital osteoarthritis.Semantic proximity Read ↗

A new Enpp1 allele, Enpp1(ttw-Ham), identified in an ICR closed colony.Semantic proximity Read ↗

Variants in genes encoding pyrophosphate metabolizing enzymes are associated with Pseudoxanthoma elasticum.Semantic proximity Read ↗

Pseudoxanthoma Elasticum, Kidney Stones and Pyrophosphate: From a Rare Disease to Urolithiasis and Vascular Calcifications.Semantic proximity Read ↗

Association of ENPP1 gene polymorphisms with hand osteoarthritis in a Chuvasha population.Semantic proximity Read ↗

Calcification of joints and arteries with novel NT5E mutations with involvement of upper extremity arteries.Semantic proximity Read ↗

Cuff tear arthropathy: evidence of functional variation in pyrophosphate metabolism genes.Semantic proximity Read ↗

Investigation of the role of ENPP1 and TNAP genes in chondrocalcinosis.Semantic proximity Read ↗

Oral supplementation of inorganic pyrophosphate in pseudoxanthoma elasticum.Semantic proximity Read ↗

Human pannexin mutations and their implications in erosive osteoarthritis.Semantic proximity Read ↗

Role of the progressive ankylosis gene in cartilage mineralization.Semantic proximity Read ↗

High-dose oral pyrophosphate inhibits connective tissue calcification in Abcc6 null mice but affects bone structureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.