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Article

Investigation of the role of ENPP1 and TNAP genes in chondrocalcinosis.

Rheumatology (Oxford, England) - 1 Apr 2007

Zhang Y, Brown M A, Peach C, Russell G, Wordsworth B P

Abstract excerpt

OBJECTIVES: Extracellular inorganic pyrophosphate (ePPi) inhibits certain forms of pathological mineralization while promoting others. Three molecules involved in ePPi regulation are important candidates for the development of calcium pyrophosphate dihydrate chondrocalcinosis (CPPD CC). These include ANKH, ectonucleotide pyrophosphatase (ENPP1) and TNAP. We have previously showed that genetic variation in ANKH is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17043047
DOI: 10.1093/rheumatology/kel338

Genes

ENPP1
ANKH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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