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Article

Mutational analysis of the GPI-anchor addition sequence from the circumsporozoite protein of Plasmodium.

Cellular microbiology - 1 Nov 2005

Wang Qian, Fujioka Hisashi, Nussenzweig Victor

Abstract excerpt

The plasma membrane of Plasmodium sporozoites is uniformly covered by the glycosylphosphatidylinositol (GPI)-anchored circumsporozoite (CS) protein. Sporozoites form in the mosquito midgut through a budding process that occurs within a multinucleate oocyst underneath the basal lamina of the gut. Earlier genetic studies established that normal sporozoite development requires CS. Mutant parasites lacking CS [CS...

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Identifiers

PMID: 16207248
DOI: 10.1111/j.1462-5822.2005.00579.x

Genes

GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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