Divergent selection for pentobarbital-induced sleeping times in mice.

doi:10.1159/000138927

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Article

Divergent selection for pentobarbital-induced sleeping times in mice.

Pharmacology - 1 Jan 1992

Stino F K

Abstract excerpt

A pharmacogenetic model for sensitivity of mice to pentobarbital is being developed by selection for sleep-time response. One generation of divergent selection for long and short sleep-time in mice resulted in a 19% increase in the long-sleep line and a 15% decrease in the short-sleep line. Calcu...

Topics

Analysis of Variance
Animals
Female
Genes
Male
Mice
Pentobarbital
Phenotype
Selection, Genetic
Sleep

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