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Article

Late onset cardiomyopathy as presenting sign of ATTR A45G amyloidosis caused by a novel TTR mutation (p.A65G).

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000

Klaassen Sebastiaan H C, Lemmink Henny H, Bijzet Johan, Glaudemans Andor W J M, Bos Reinhard, Plattel Wouter, van den Berg Maarten P, Slart Riemer H J A, Nienhuis Hans L A, van Veldhuisen Dirk J, Hazenberg Bouke P C

Abstract excerpt

OBJECTIVE: The clinical description of a novel TTR gene mutation characterized by a late onset amyloid cardiomyopathy. METHODS AND RESULTS: A 78-year-old man of Dutch origin with recent surgery for bilateral carpal tunnel syndrome (CTS) was admitted to our hospital because of heart failure with preserved ejection fraction (55%). Cardiac ultrasound showed thickened biventricular walls, and cardiac magnetic...

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Source

Identifiers

PMID: 28460244
DOI: 10.1016/j.carpath.2017.04.002

Genes

TTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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