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Article

Personalized Therapy in Pain Management: Where Do We Stand?

27 May 2010

Abstract excerpt

Genomic variations influencing response to pharmacotherapy of pain are currently under investigation. Drug-metabolizing enzymes represent a major target of ongoing research in order to identify associations between an individual's drug response and genetic profile. Polymorphisms of the cytochrome P450 enzymes (CYP2D6) influence metabolism of codeine, tramadol, hydrocodone, oxycodone and tricyclic antidepressants....

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Share to Pain Management and Opioid Use
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Identifiers

PMID: 20504256
DOI: 10.2217/pgs.10.47

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