Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative genomic hybridization and BUB1B mutation analyses in childhood cancers associated with mosaic variegated aneuploidy syndrome.

Cancer letters - 8 Aug 2006

Hanks Sandra, Coleman Kim, Summersgill Brenda, Messahel Boo, Williamson Dan, Pritchard-Jones Kathryn, Strefford Jon, Swansbury John, Plaja Alberto, Shipley Janet, Rahman Nazneen

Abstract excerpt

We previously demonstrated that constitutional BUB1B mutations cause mosaic variegated aneuploidy, a condition characterized by constitutional aneuploidies and childhood cancer predisposition. To further investigate the role of BUB1B in cancer predisposition we performed comparative genomic hybridization analysis in an embryonal rhabdomyosarcoma from an MVA case with biallelic BUB1B mutations, revealing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aneuploidy
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mosaicism

Share to Mutation

Share to Neoplasms

Share to Nucleic Acid Hybridization

Share to Protein Kinases

Share to Protein Serine-Threonine Kinases

Source

Identifiers

PMID: 16182441
DOI: 10.1016/j.canlet.2005.08.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative genomic hybridization and BUB1B mutation analyses in childhood cancers associated with mosaic variegated aneuploidy syndrome.PMID 16182441Read ↗

Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B.Semantic proximity Read ↗

Clinical and genetic heterogeneity in patients with mosaic variegated aneuploidy: delineation of clinical subtypes.Semantic proximity Read ↗

Pathogenic correlation between mosaic variegated aneuploidy 1 (MVA1) and a novel BUB1B variant: a reappraisal of a severe syndrome.Semantic proximity Read ↗

Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy.Semantic proximity Read ↗

TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of BUB1B as causative of PCS (MVA) syndrome.Semantic proximity Read ↗

Child with mosaic variegated aneuploidy and embryonal rhabdomyosarcomaSemantic proximity Read ↗

BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.Semantic proximity Read ↗

Aneuploidy-Cancer Predisposition Syndromes: A New Link between the Mitotic Spindle Checkpoint and CancerSemantic proximity Read ↗

CEP57 mutation in a girl with mosaic variegated aneuploidy syndrome.Semantic proximity Read ↗

Combined BubR1 protein down-regulation and RASSF1A hypermethylation in Wilms tumors with diverse cytogenetic changes.Semantic proximity Read ↗

Aneuploidy-cancer predisposition syndromes: a new link between the mitotic spindle checkpoint and cancer.Semantic proximity Read ↗

Homozygous BUB1B mutation and susceptibility to gastrointestinal neoplasia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.