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Article

Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport.

Pharmaceutical research - 1 Oct 2005

Ito Kousei, Suzuki Hiroshi, Horie Toshiharu, Sugiyama Yuichi

Abstract excerpt

It is well known that transporter proteins play a key role in governing drug absorption, distribution, and elimination in the body, and, accordingly, they are now considered as causes of drug-drug interactions and interindividual differences in pharmacokinetic profiles. Polarized tissues directly involved in drug disposition (intestine, kidney, and liver) and restricted distribution to naive sanctuaries...

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Source

Identifiers

PMID: 16180115
DOI: 10.1007/s11095-005-6810-2

Genes

ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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