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Article

The importance of the phagocytes' innate response in resolution of the infection induced by a low virulent Candida albicans mutant.

Scandinavian journal of immunology - 1 Sept 2005

Molero G, Guillén M V, Martínez-Solano L, Gil C, Pla J, Nombela C, Sánchez-Pérez M, Diez-Orejas R

Abstract excerpt

We have reported that a Candida albicans mkc1Delta/mkc1Delta mutant, deleted in the Mkc1p mitogen-activated protein kinase, an essential element of the cell integrity signalling pathway, has reduced virulence in a murine model of systemic infection. We analyse here the immunological basis for this feature in view of its failure to vaccinate. Firstly, the influence of the Th response was analysed by infecting...

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PMID: 16179009
DOI: 10.1111/j.1365-3083.2005.01657.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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