Article
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism - 1 Dec 2005
Xing Mingzhao, Westra William H, Tufano Ralph P, Cohen Yoram, Rosenbaum Eli, Rhoden Kerry J, Carson Kathryn A, Vasko Vasily, Larin Alexandr, Tallini Giovanni, Tolaney Sara, Holt Elizabeth H, Hui Pei, Umbricht Christopher B, Basaria Shehzad, Ewertz Marge, Tufaro Anthony P, Califano Joseph A, Ringel Matthew D, Zeiger Martha A, Sidransky David, Ladenson Paul W
Abstract excerpt
CONTEXT: Use of BRAF mutation in papillary thyroid cancer (PTC) has the potential to improve risk stratification of this cancer. OBJECTIVE: The objective of the study was to investigate the prognostic value of BRAF mutation in patients with PTC. DESIGN, SETTING, AND SUBJECTS: In a multicenter study of 219 PTC patients, data on their clinicopathological characteristics and clinical courses between 1990 and 2004...
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