Article
Campylobacter gene polymorphism as a determinant of clinical features of Guillain-Barré syndrome.
Neurology - 8 Nov 2005
Koga M, Takahashi M, Masuda M, Hirata K, Yuki N
Abstract excerpt
BACKGROUND: Ganglioside epitopes on Campylobacter jejuni are hypothesized as the key to the development and characterization of Guillain-Barré syndrome (GBS), but a comprehensive theory has yet to be established. A C jejuni gene, cst-II, involved in the biosynthesis of ganglioside-like lipo-oligosaccharide, shows a polymorphism (Asn/Thr51) that affects ganglioside epitopes. OBJECTIVE: To examine the hypothesis...
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