Article
Polymorphism of Fas and Fas ligand in preterm premature rupture of membranes in singleton pregnancies.
American journal of obstetrics and gynecology - 1 Sept 2005
Fuks Aleksandr, Parton Lance A, Polavarapu Satya, Netta Denise, Strassberg Sonya, Godi Ioana, Hsu Chaur-Dong
Abstract excerpt
OBJECTIVE: Fetal inflammatory response has been previously shown to be involved in the pathogenesis of preterm premature rupture of membranes. We investigated the association between polymorphisms at position -670 in the Fas gene and position -124 in the Fas ligand gene demonstrated in neonatal oral mucosa cells and preterm premature rupture of membranes. STUDY DESIGN: Thirty-six singleton pregnancies were...
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