Article
Low-molecular-weight fucoidan enhances the proangiogenic phenotype of endothelial progenitor cells.
Biochemical pharmacology - 15 Oct 2005
Zemani Faouzia, Benisvy Danielle, Galy-Fauroux Isabelle, Lokajczyk Anna, Colliec-Jouault Sylvia, Uzan Georges, Fischer Anne Marie, Boisson-Vidal Catherine
Abstract excerpt
Endothelial progenitor cell (EPC) transplantation is a potential means of inducing neovascularization in vivo. However, the number of circulating EPC is relatively small, it may thus be necessary to enhance their proangiogenic properties ex vivo prior to injection in vivo. Fucoidan has previously been shown to potentiate in vitro tube formation by mature endothelial cells in the presence of basic fibroblast...
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