Article
Factors regulating condylar cartilage growth under repeated load application.
Frontiers in bioscience : a journal and virtual library - 1 Jan 2006
Ng A F S, Yang Y O, Wong R W K, Hägg E U O, Rabie A B M
Abstract excerpt
Mechanical loading can influence the biological behavior of the bone-associated cells leading to adaptive changes in skeletal mass and architecture. SOX9 and PTHrP genes are known to regulate chondrocyte differentiation and delay maturation, ultimately control the endochondral bone formation. To investigate the effects of repeated mechanical loading on bone, 280 Sprague-Dawley rats were used in this experiment....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
