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Article

Characterization of the human MDR1 gene.

The AAPS journal - 16 Feb 2005

Bodor Miklos, Kelly Edward J, Ho Rodney J

Abstract excerpt

P-glycoprotein (Pgp), an ATP-dependent efflux transporter that protects the body from environmental toxins and xenobiotics, is encoded by the human MDR1 gene. Human MDR1 is located on chromosomal region 7q21. Although several different single nucleotide polymorphisms were shown to influence Pgp expression and activity, the reported length of the MDR1 gene in Genbank and other databases continues to evolve and...

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Identifiers

PMID: 16146331
DOI: 10.1208/aapsj070101
PMCID: PMC2751491

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