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Article

Developmental pesticide models of the Parkinson disease phenotype.

Environmental health perspectives - 1 Sept 2005

Cory-Slechta Deborah A, Thiruchelvam Mona, Barlow Brian K, Richfield Eric K

Abstract excerpt

It has been hypothesized that developmental insults could contribute to Parkinson disease (PD), a neurodegenerative disorder resulting from the loss of the dopamine neurons of the nigrostriatal pathway. Two models of developmental pesticide exposures in mice are presented here that yield PD phenotypes consistent with this possibility. Combined exposures to the herbicide paraquat (PQ) and the fungicide maneb (MB),...

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Source

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Identifiers

PMID: 16140639
DOI: 10.1289/ehp.7570
PMCID: PMC1280413

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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