Article
Electrophysiological basis and genetics of Brugada syndrome.
Journal of cardiovascular electrophysiology - 1 Sept 2005
Grant Augustus O
Abstract excerpt
Brugada syndrome is a primary arrhythmic syndrome arising in the structurally normal heart. Any proposed mechanism should account for the major features of the syndrome: localization of the ST segment and T-wave changes to the right precordial leads, association of conduction slowing at several levels, precipitation or aggravation of the major ECG changes by sodium channel-blocking drugs and the occurrence of...
Topics
- Bundle-Branch Block
- Electrocardiography
- Genetic Predisposition to Disease
- Heart Conduction System
- Humans
- Ion Channel Gating
- Muscle Proteins
- NAV1.5 Voltage-Gated Sodium Channel
- Polymorphism, Genetic
- Sodium Channels
- Syndrome