Article
Platelet-mimicry of cancer cells: epiphenomenon with clinical significance.
Oncology - 1 Jan 2005
Tímár József, Tóvári József, Rásó Erzsébet, Mészáros Livia, Bereczky Bíborka, Lapis Károly
Abstract excerpt
Stem cell mimicry of cancer cells has been known for a long time and is considered to be responsible for ectopic gene expressions. The stem cell characteristics of tumor cells are shown to be involved in epithelial-mesenchymal transition and in the phenomenon of vascular mimicry. Certain cancer types acquire a geno-phenotype closely resembling the platelets and express several megakaryocytic genes (adhesion...
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