Article
Significance of a common single nucleotide polymorphism in exon 10 of the follicle-stimulating hormone (FSH) receptor gene for the ovarian response to FSH: a pharmacogenetic approach to controlled ovarian hyperstimulation.
Pharmacogenetics and genomics - 1 Jul 2005
Behre Hermann M, Greb Robert R, Mempel Andrea, Sonntag Barbara, Kiesel Ludwig, Kaltwasser Petra, Seliger Ewald, Röpke Friedrich, Gromoll Jörg, Nieschlag Eberhard, Simoni Manuela
Abstract excerpt
The p.N680S sequence variation of the follicle-stimulating hormone (FSH) receptor gene was previously shown to influence the ovarian response to FSH in normo-ovulatory women undergoing controlled ovarian hyperstimulation. In this prospective, randomized, controlled study, we tested whether the same daily dose of FSH results in lower levels of oestradiol in women homozygous for the p.N680S sequence variation, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.