Article
Infectious pancreatic necrosis virus induces apoptosis in vitro and in vivo independent of VP5 expression.
Virology - 10 Nov 2005
Santi Nina, Sandtrø Ane, Sindre Hilde, Song Haichen, Hong Jiann-Ruey, Thu Beate, Wu Jen-Leih, Vakharia Vikram N, Evensen Øystein
Abstract excerpt
Infectious pancreatic necrosis virus (IPNV), the causative agent of a highly infectious disease in salmonid fish, encodes a small non-structural protein designated VP5. This protein contains Bcl-2 homologous domains and inhibits apoptosis when expressed in cell culture. We have previously reporte...
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