Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A dominant negative form of Rac1 affects myogenesis of adult thoracic muscles in Drosophila.

Developmental biology - 1 Sept 2005

Fernandes Joyce J, Atreya Krishan B, Desai Krishna M, Hall Rachel E, Patel Meatal D, Desai Amita A, Benham Amy E, Mable Jessica L, Straessle Jennifer L

Abstract excerpt

Blocking Rac1 function in precursors of the indirect flight muscle of Drosophila severely disrupts muscle formation. The DLM fibers that develop using larval scaffolds are reduced in number and fiber size, while the DVMs, which develop using founder cells, are mostly absent. These adult muscle phenotypes are in part due to a reduced myoblast pool present at the third larval instar. BrDU labeling studies indicated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Fusion
Share to Flight, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Targeting

Share to Genes, Insect

Share to Muscle Development

Share to Myoblasts, Skeletal

Share to rac GTP-Binding Proteins

Share to Wings, Animal

Source

Identifiers

PMID: 16125691
DOI: 10.1016/j.ydbio.2005.05.040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A dominant negative form of Rac1 affects myogenesis of adult thoracic muscles in Drosophila.PMID 16125691Read ↗

Rab11 is required for myoblast fusion in Drosophila.Semantic proximity Read ↗

Identification of Rho GTPases implicated in terminal differentiation of muscle cells in ascidia.Semantic proximity Read ↗

Drosophila Rac1 controls motor axon guidance.Semantic proximity Read ↗

Distinct effects of Rac1 on differentiation of primary avian myoblasts.Semantic proximity Read ↗

The formation of syncytia within the visceral musculature of the Drosophila midgut is dependent on duf, sns and mbc.Semantic proximity Read ↗

Effect of myonuclear number and mitochondrial fusion on Drosophila indirect flight muscle organization and size.Semantic proximity Read ↗

A direct screen identifies new flight muscle mutants on the Drosophila second chromosome.Semantic proximity Read ↗

Twist is required for muscle template splitting during adult Drosophila myogenesis.Semantic proximity Read ↗

Myoblast diversification and ectodermal signaling in Drosophila.Semantic proximity Read ↗

Basic methods for Drosophila muscle biology.Semantic proximity Read ↗

The muscleblind gene participates in the organization of Z-bands and epidermal attachments of Drosophila muscles and is regulated by Dmef2.Semantic proximity Read ↗

Muscle development is independent of innervation during Drosophila embryogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.