Article
Differential myocardial infarct repair with muscle stem cells compared to myoblasts.
Molecular therapy : the journal of the American Society of Gene Therapy - 1 Dec 2005
Oshima Hideki, Payne Thomas R, Urish Kenneth L, Sakai Tetsuro, Ling Yiqun, Gharaibeh Burhan, Tobita Kimimasa, Keller Bradley B, Cummins James H, Huard Johnny
Abstract excerpt
Myoblast transplantation for cardiac repair has generated beneficial results in both animals and humans; however, poor viability and poor engraftment of myoblasts after implantation in vivo limit their regeneration capacity. We and others have identified and isolated a subpopulation of skeletal muscle-derived stem cells (MDSCs) that regenerate skeletal muscle more effectively than myoblasts. Here we report that...
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