Article
[Generation of RHD-CE(2-9)-D allele by gene conversion in cis].
Yi chuan = Hereditas - 1 Jul 2005
Shao Chao-Peng, Li Zhen, Xiong Wen, Zhou Yi-Yan, Li Xue-Mei
Abstract excerpt
Previously a few Rh-negative individuals in Caucasian and Chinese were found existing exons 1 and 10 of RHD through genomic DNA testing. The molecular mechanisms, however, remain disputed. In this study, 2 individuals carrying RHD positive, D antigen negative allele (with exon 1 and 10 of RHD) and their mRNA were investigated by using reverse transcriptase PCR (RT-PCR) and sequencing through one pair of specific...
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