Article
The implication of somatotroph adenoma phenotype to somatostatin analog responsiveness in acromegaly.
The Journal of clinical endocrinology and metabolism - 1 Nov 2005
Bhayana Shelly, Booth Gillian L, Asa Sylvia L, Kovacs Kalman, Ezzat Shereen
Abstract excerpt
CONTEXT: Persistently elevated GH and IGF-I levels are associated with increased mortality. Their response to somatostatin analogs (SSA) is variable. OBJECTIVE: The objective of this study was to examine the significance of somatotroph adenoma type on response to SSA. DESIGN: This study was a retrospective examination of postoperatively treated acromegalic patients with the SSA octreotide. SETTING: The study was...
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