Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Examination of the coordinate effects of Pseudomonas aeruginosa ExoS on Rac1.

Infection and immunity - 1 Sept 2005

Rocha Claudia L, Rucks Elizabeth A, Vincent Deanne M, Olson Joan C

Abstract excerpt

Exoenzyme S (ExoS) is a bifunctional toxin directly translocated into eukaryotic cells by the Pseudomonas aeruginosa type III secretory (TTS) process. The amino-terminal GTPase-activating (GAP) activity and the carboxy-terminal ADP-ribosyltransferase (ADPRT) activity of ExoS have been found to target but exert opposite effects on the same low-molecular-weight G protein, Rac1. ExoS ADP-ribosylation of Rac1 is cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to NIH 3T3 Cells
Share to p21-Activated Kinases
Share to Adenosine Diphosphate Ribose

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ADP Ribose Transferases

Share to HT29 Cells

Share to Jurkat Cells

Share to rac GTP-Binding Proteins

Share to Vero Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 16113262
DOI: 10.1128/IAI.73.9.5458-5467.2005
PMCID: PMC1231149

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Examination of the coordinate effects of Pseudomonas aeruginosa ExoS on Rac1.PMID 16113262Read ↗

Independent and coordinate effects of ADP-ribosyltransferase and GTPase-activating activities of exoenzyme S on HT-29 epithelial cell function.Semantic proximity Read ↗

Plasma membrane localization affects the RhoGAP specificity of Pseudomonas ExoS.Semantic proximity Read ↗

A leucine-rich motif targets Pseudomonas aeruginosa ExoS within mammalian cells.Semantic proximity Read ↗

Pseudomonas aeruginosa ExoT ADP-ribosylates CT10 regulator of kinase (Crk) proteins.Semantic proximity Read ↗

ADP-ribosylation by exoenzyme T of Pseudomonas aeruginosa induces an irreversible effect on the host cell cytoskeleton in vivo.Semantic proximity Read ↗

GPR107, a G-protein-coupled receptor essential for intoxication by Pseudomonas aeruginosa exotoxin A, localizes to the Golgi and is cleaved by furin.Semantic proximity Read ↗

ExoS and ExoT ADP Ribosyltransferase Activities Mediate Pseudomonas aeruginosa Keratitis by Promoting Neutrophil Apoptosis and Bacterial SurvivalSemantic proximity Read ↗

Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis.Semantic proximity Read ↗

Actin cytoskeleton disruption by ExoY and its effects on Pseudomonas aeruginosa invasion.Semantic proximity Read ↗

Expression ofPseudomonas aeruginosaToxin ExoS Effectively Induces Apoptosis in Host CellsSemantic proximity Read ↗

ExoS effector in Pseudomonas aeruginosa Hyperactive Type III secretion system mutant promotes enhanced Plasma Membrane Rupture in Neutrophils.Semantic proximity Read ↗

Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.