Article
Infection with a periodontal pathogen induces procoagulant effects in human aortic endothelial cells.
Journal of thrombosis and haemostasis : JTH - 1 Oct 2006
Roth G A, Moser B, Huang S J, Brandt J S, Huang Y, Papapanou P N, Schmidt A M, Lalla E
Abstract excerpt
BACKGROUND: Multiple studies have demonstrated a link between periodontal infections and vascular disease. Porphyromonas gingivalis, a major periodontal pathogen, has been shown to adhere to and invade endothelial cells. OBJECTIVE: In order to dissect mechanisms underlying these observations, we assessed the role of P. gingivalis infection in modulating properties of endothelial cells linked to atherothrombosis....
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