Article
MDR1, MRP1 and MRP2 genotypes and in vitro chemosensitivity in Japanese patients with colorectal adenocarcinomas.
The Kobe journal of medical sciences - 1 Jan 2004
Nishioka Chiharu, Sakaeda Toshiyuki, Nakamura Tsutomu, Moriya Yuka, Okamura Noboru, Tamura Takao, Nakahara Takako, Aoyama Nobuo, Kamigaki Takashi, Ohno Masakazu, Kuroda Yoshikazu, Kasuga Masato, Okumura Katsuhiko
Abstract excerpt
In our previous paper, the chemosensitivity of human colorectal adenocarcinoma was evaluated against 12 anticancer drugs including 5-fluorouracil (5-FU), 7-ethyl-10-hydroxycamptothecin (SN-38), mitomycin C (MMC) and cisplatin (CDDP), and it was found that the anticancer drugs were effective against those with a relatively high growth rate. MMC was effective for those with a relatively high mRNA expression of the...
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