Article
Transgenic animal methodologies and their applications.
Human cell - 1 Sept 1993
Gordon J W, Harold G, Leila Y
Abstract excerpt
In the past 10 years the capacity has been acquired to genetically transform mammals via insertion of genes into developmentally totipotent embryonic cells. This profound advance has impacted significantly on our understanding of basic mechanisms of gene regulation, and has enabled practitioner's of this "transgenic technology" to establish important paradigms for the genetic engineering of experimental animals...
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