Article
Evidence that WbpD is an N-acetyltransferase belonging to the hexapeptide acyltransferase superfamily and an important protein for O-antigen biosynthesis in Pseudomonas aeruginosa PAO1.
Molecular microbiology - 1 Sept 2005
Wenzel Cory Q, Daniels Craig, Keates Robert A B, Brewer Dyanne, Lam Joseph S
Abstract excerpt
Di-N-acetylated uronic acid residues are unique sugar moieties observed in the lipopolysaccharides (LPS) of respiratory pathogens including several serotypes of Pseudomonas aeruginosa and several species of Bordetella. WbpD of P. aeruginosa PAO1 (serotype O5) is a putative 3-N-acetyltransferase that has been implicated in the biosynthesis of UDP-2,3-diacetamido-2,3-dideoxy-d-mannuronic acid...
Topics
- Acetyl Coenzyme A
- Acetyltransferases
- Amino Acid Sequence
- Models, Molecular
- Molecular Sequence Data
- Mutation
- O Antigens
- Protein Structure, Secondary
- Protein Structure, Tertiary
- Pseudomonas aeruginosa