Article
Structural analysis of WbpE from Pseudomonas aeruginosa PAO1: a nucleotide sugar aminotransferase involved in O-antigen assembly.
Biochemistry - 24 Aug 2010
Larkin Angelyn, Olivier Nelson B, Imperiali Barbara
Abstract excerpt
In recent years, the opportunistic pathogen Pseudomonas aeruginosa has emerged as a major source of hospital-acquired infections. Effective treatment has proven increasingly difficult due to the spread of multidrug resistant strains and thus requires a deeper understanding of the biochemical mech...
Topics
- Alanine
- Crystallography, X-Ray
- Models, Molecular
- Mutation
- Nitrogenous Group Transferases
- O Antigens
- Protein Binding
- Pseudomonas Infections
- Pseudomonas aeruginosa
- Pyridoxal Phosphate
- Pyridoxamine
- Schiff Bases
- Uridine Diphosphate Glucuronic Acid