Article
Structural analysis of WbpE from Pseudomonas aeruginosa PAO1: a nucleotide sugar aminotransferase involved in O-antigen assembly.
Biochemistry - 24 Aug 2010
Larkin Angelyn, Olivier Nelson B, Imperiali Barbara
Abstract excerpt
In recent years, the opportunistic pathogen Pseudomonas aeruginosa has emerged as a major source of hospital-acquired infections. Effective treatment has proven increasingly difficult due to the spread of multidrug resistant strains and thus requires a deeper understanding of the biochemical mechanisms of pathogenicity. The central carbohydrate of the P. aeruginosa PAO1 (O5) B-band O-antigen, ManNAc(3NAc)A, has...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
